Blood Plasma Fractionation Plant

SYNCS together with alliance C&S Process designed, manufactured and commissioned a complete plant for blood plasma fractionation. It was a turn key solution with delivery term of EPC including the process equipment, control system, hygienic and clean rooms, HVAC, building architecture, structures, utilities, drainage, surveillance system and ground foundation.

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SYNCS provided the full detailed design, fabrication, logistics, site construction, commissioning and validation services for the full blood plasma fractionation plant.

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The blood plasma fractionation including: viral inactivation workshop, flexible separation and purification workshops, workshop for in-place decontamination of separation equipment, buffer preparation, CIP, in-place sterilization, automation, Nano-filtration sensor module.

Scope of Supply in Equipments

• Frozen plasma dissolution

• Fractionation for Albumin and Globulin

• Buffer preparation

• Albumin UF purification and Pasteurization

• IVIG ETOH

• IVIG Chromo

• IMIG

• Prothrombin Complex (PCC)  adsorption, solvent detergent (SD) treatment

• Fibrinogen SD treatment

• Factor VIII SD treatment

• CIP + TCU

Scope Matrix

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Benefits of Full Modular Plant:

Schedule - Shorten

• Plant construction and Site Construction progress simultaneously

• Reduced Design Time

• Reduced Overall Project Schedule

• Normally ONE MONTH for Site Installation

Quality - Ensured

• In House Fabrication

• Controlled Environment

• Highly Skilled Workforce

• High Standard QA System

• Continuous Improvement via repetitive executions

• FAT for whole Plant

HSE Conduct  - Improved

• Eliminate Risks and Hazardous at Site

• Reduced Construction Setting up Time

• Minimised Impact to the Environment

 Client Efforts Minimised

• Less Interfaces

• Single Point of Responsibility, One Stop Solution

• Fixed execution model for world wide application

• Use available expertise to consider on behalf of the client

Cost - Reduced

• Minimised Client Management Cost

• Avoid Scope Missing/Overlapping and Waste

• Reduced cost from reduced time for Design and Construction

• Utilised Low Labour Cost

• Early production generates early launch to market

• Modular Plant is RELOCATABLE, Increase Asset Life Cycle Value


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